Molecular Building Block

Your Professional Molecular Building Block Supplier！

We are Aeechem, a global leader in the research, development, and production of high-value pharmaceutical intermediates and building blocks. Headquartered in Nanjing, China, with a dedicated R&D center and GMP-compliant manufacturing in India, we combine custom synthesis expertise with scalable production to empower innovative biotech and pharma companies worldwide.

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Why Choose Us

Manufacturing Capability

Aeechem supports the full development process from laboratory research to commercial-scale production.From milligram samples for early-stage research to multi-ton commercial production, our integrated, GMP-compliant facilities ensure seamless scale-up and consistent quality.

Reliable Supply

The importance of timely delivery and clear communication in pharmaceutical sourcing. By combining responsive technical support with flexible production capacity, Aeechem serves customers across global markets with dependable project execution and long-term supply stability.

Advanced technology

Aeechem focuses on high-value intermediates and complex building blocks for innovative drug development. Our continuous investment in research and proprietary molecules allows customers to access a growing portfolio of advanced compounds for both R&D and commercial needs.

Common types

We offers the following product introduce:

Tert-Butyl 6-cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate

N-(5-(3-(7-(3-Fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl)-1H-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide

N-(3,5-Bis(trifluoromethyl)phenyl)hydrazinecarbothioamide

Boronates and Boric Acids
Boronates are esters and salts of boronic acid. Boronic acid is a compound related to boric acid in which one of the three hydroxyl groups has been replaced by either an alkyl or an aryl group.

Aromatic Ring
Aromatic rings refer to cyclic structures that contain delocalized π-electrons, which contribute to their stability and unique electronic properties. In the context of organic D-π-A compounds, aromatic rings can enhance second harmonic generation (SHG) effects by stabilizing the π-medium and facilitating π-π* electronic transitions.

Heteroaromatic Ring
A heterocyclic compound or ring structure is a hydrocarbon-based cyclic compound that contains at least one heteroatom as member(s) of its ring(s). Heterocyclic organic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of organic heterocycles.

Fluorinated Building Blocks
Fluorinated building blocks are a class of organic compounds containing fluorine atoms or fluorine-containing groups, and often used in the synthesis of fluorinated compounds. They usually appear in the form of monofluoro, difluoro or trifluoro in the chemical structures, such as monofluoromethyl, difluoromethyl, trifluoromethyl. Due to the high electronegativity, small atomic radius and high polarizability of fluorine, fluorinated building blocks exhibit unique chemical, physical and biomedical properties.

Product Specification

Product Name	5-Acetyl-1,3-phenylene diacetate
CAS Number	35086-59-0
Molecular Formula	C12H12O5
Molecular Weight	236.22
SMILES Code	O=C(C1=CC(OC(C)=O)=CC(OC(C)=O)=C1)C
MDL No.	MFCD00008702
Product Name	1,8-Dichloroanthracene-9,10-dione
CAS Number	82-43-9
Molecular Formula	C14H6Cl2O2
Molecular Weight	277.1
SMILES Code	O=C1C2=C(C=CC=C2Cl)C(C3=CC=CC(Cl)=C13)=O
MDL No.	MFCD00001191

Application

5-Acetyl-1,3-phenylene Diacetate

Pharmaceutical Building Block

Derivatives of this scaffold have been explored in the synthesis of anti-inflammatory and antimicrobial agents. The 1,3-diacetoxyphenyl motif appears in natural products and drug candidates where the phenolic acetates can act as prodrug moieties, releasing the active catechol-type structure upon enzymatic hydrolysis. The acetyl group provides a handle for introducing additional pharmacophoric elements via Claisen condensation or related reactions.

Polymer and Materials Chemistry

The trifunctional nature of this compound makes it valuable as a crosslinking monomer or chain extender in polyester and polyurethane synthesis. The acetyl groups can participate in transesterification reactions, while the aromatic core imparts rigidity and thermal stability. Such materials are investigated for coatings, adhesives, and high-performance polymers where controlled crosslink density is required.

1,4-Naphthoquinone

Pharmaceutical Intermediate

This naphthoquinone serves as a key building block in the synthesis of various therapeutic agents, including antimalarial and anticancer drugs. The quinone core appears in natural products such as lapachol and lawsone, which have demonstrated cytotoxic activity against tumor cells. Derivatives of 1,4-naphthoquinone are investigated for their ability to inhibit topoisomerases and generate oxidative stress in cancer cells, leading to apoptosis. Menadione (vitamin K₃), a synthetic derivative, is used as a prothrombotic agent and nutritional supplement.

Dye and Pigment Intermediate

1,4-Naphthoquinone is utilized in the production of vat dyes and disperse dyes, where its quinoid structure contributes to intense coloration. The compound can be functionalized with amino, hydroxy, and other substituents to generate dyes with varying shades ranging from yellow to violet. These dyes exhibit good lightfastness and are employed in textile dyeing and printing applications.

Certifications

Package & Delivery

Package: Standard export package or Custom
Delivery: By air express, by sea

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FAQ

Q: What types of molecular building blocks does Aeechem provide?

A: Aeechem supplies a wide range of pharmaceutical building blocks, including heterocyclic compounds, boronic acids, chiral intermediates, fluorinated compounds, and other advanced intermediates used in drug discovery and API development.

Q: Can you support both research and commercial quantities?

A: Yes. We support projects from milligram and gram-scale quantities for early-stage research to kilogram and multi-ton production for commercial manufacturing.

Q: Are your products suitable for pharmaceutical applications?

A: Our building blocks are developed for pharmaceutical and biotech applications, with production supported by GMP-compliant manufacturing facilities and controlled quality systems.

Q: Do you offer custom synthesis services?

A: Yes. In addition to catalog products, we provide custom synthesis services for novel compounds, complex intermediates, and process development projects based on customer specifications.

Q: How do you ensure product quality and batch consistency?

A: We apply strict quality control procedures throughout development and manufacturing, including analytical testing, impurity monitoring, and batch documentation to ensure consistent product performance.

Q: Can you provide analytical data with the products?

A: Yes. Standard analytical documents such as COA, HPLC, NMR, MS, and other supporting data can be provided according to project requirements.

Q: What industries commonly use your molecular building blocks?

A: Our products are widely used by pharmaceutical companies, biotech firms, CROs, CDMOs, and research institutions involved in small molecule drug development.

Q: Do you support confidential development projects?

A: Yes. We understand the importance of intellectual property protection and work under strict confidentiality agreements for custom synthesis and collaborative development projects.

Q: How quickly can you deliver research samples?

A: Lead times depend on product availability and synthesis complexity. For many catalog compounds, research quantities can be supplied within a short production cycle.

Q: Can Aeechem handle difficult or complex chemistries?

A: Our team has experience in multi-step synthesis, heterocyclic chemistry, fluorination, chiral chemistry, and other technically challenging processes commonly required in pharmaceutical development.

Q: Do you provide process optimization for scale-up projects?

A: Yes. Our R&D and manufacturing teams work together to optimize synthetic routes, improve process efficiency, and support smooth scale-up from laboratory to commercial production.

Q: What is your advantage in global supply support?

A: With R&D operations in China and manufacturing capabilities in India, Aeechem provides flexible production planning and stable supply support for customers in multiple international markets.

Q: Are your building blocks available as catalog products?

A: Yes. We continuously expand our catalog with new and proprietary compounds to support evolving drug discovery and development needs.

Q: How do you manage regulatory and documentation requirements?

A: We support customers with relevant technical documentation and work closely with clients to meet project-specific quality and regulatory expectations.

Q: Why do pharmaceutical companies choose Aeechem as a supplier?

A: Customers value Aeechem for its combination of technical expertise, scalable manufacturing, responsive communication, and reliable long-term supply support for complex pharmaceutical intermediates and building blocks.

As one of the leading molecular building block manufacturers and suppliers in China, we also support customized service. Please feel free to buy high quality molecular building block made in China here from our factory. For quotation and free sample, contact us now.